Research roundup
Take a look at some of the published research to come out of the Children's Diabetes Centre recently.
- Diabetes and exercise management is complex, and many factors can influence an individual's glycaemic response to exercise. Consequently, it can be challenging for healthcare practitioners to advise young people with type 1 how to approach exercise safely. This collaborative review provides a structured approach to exercise consultation to assist healthcare professionals in formulating individual exercise management plans for young people with type 1 diabetes. Article: https://www.frontiersin.org/articles/10.3389/fendo.2019.00326/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE
- Pump therapy in children with type 1 diabetes is associated with better lipid profiles that serve as an initial screening tool for lipid abnormalities including cholesterol, according to new Children’s Diabetes Centre research. Centre co-director Professor Liz Davis said a cross‐sectional analysis of the lipid profile of children aged less than 18 years with type 1 diabetes was conducted with a focus on the effect of the treatment regimen: pump versus injection therapy. The collaborative study, which was published in the Diabetic Medicine journal, used patient data from SWEET, an international diabetes database. Abstract: https://onlinelibrary.wiley.com/doi/abs/10.1111/dme.13963
- New Children’s Diabetes Centre research has found it is not cost effective to use human leukocyte antigen typing as a first‐line screening test for coeliac disease in children with type 1 diabetes. The results of the study were published in the Pediatric Diabetes journal. Abstract: https://onlinelibrary.wiley.com/doi/abs/10.1111/pedi.12857
- A new strategy for vascular complications in young people with type 1 diabetes is needed, according to Children’s Diabetes Centre‘s Professor Tim Jones and his fellow Adolescent type 1 Diabetes cardio-renal Intervention Trial (AdDIT) colleagues. “Poor glycaemic control and consequent increased HbA1C levels are major risk factors for the development of vascular complications,” Professor Jones said. “HbA1c levels are the main focus of current management strategies; however, the recommended target is rarely achieved in adolescents. Thus, a clear need exists for improved biomarkers to identify high-risk young people early and to develop new intervention strategies.” AdDIT is a multi-centre, international study that is exploring the risk for kidney, eye and cardiovascular disease during puberty and if drugs already used to lower blood pressure and cholesterol levels in adults with diabetes can reduce the development of vascular complications in young people with type 1 diabetes. The commentary was published in the prestigious Nature Reviews Endocrinology journal. Abstract: https://www.nature.com/articles/s41574-019-0198-2
First published Tuesday 11 June 2019.