People with diabetes work out how much insulin to give for meals based on how much carbohydrate they plan to eat and their insulin-to-carb ratio. This ratio is based on the idea that as the carbs amount increases, so does the insulin dose linearly.
Studies suggest that the relationship might not be linear and that a different ratio might decrease the risk of “hypos” and improve glucose levels after eating. We hope this study will help people with diabetes by giving more information on the best way to calculate their insulin doses before eating common carbohydrate meals.
If you participate in the study you will wear a Dexcom G4 sensor which tracks your blood glucose levels throughout the day. While wearing the sensor, you will give your insulin in your usual way and eat pancakes with maple syrup four mornings in a row. Each pancake meal is the same but the amount of carbohydrate in the meal changes from 20g up to 150g of carbohydrates.
After eating the pancakes you will be asked not to eat or exercise for the next five hours while you do normal activities such as going to school, work, reading, writing or watching movies. You can come to Princess Margaret Hospital or the researcher can come to your home. The four study visits take approximately 30 minutes each.
We are looking for people who:
Are aged between 12-30 years
Have had T1DM for more than a year
Are on a pump or multiple daily injections with a HbA1c <8%