Dr Charles Czank completed his undergraduate and doctorate degrees in biochemistry at the University of Western Australia. After completing his studies Dr Czank worked as a postdoctoral research associate in Nutritional Biochemistry at the University East Anglia in Norwich in the UK, where he undertook research into the protective effective of dietary polyphenols against cardiovascular disease.
This was followed by industry appointments as principal scientist at Leatherhead Food Research (Surrey, UK) and project manager at Linear Clinical Research (Perth, WA), where he managed clinical research studies in a variety of areas including, nutrition, diabetes, obesity, oncology, dermatology, nephrology and infectious disease.
Dr Czank brings his experience in clinical research in both industry and academia to his position of research manager for the Diabetes and Obesity Research Group at the Telethon Kids Institute where he oversees a range of studies of treatments for these diseases.
Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study C Czank, A Cassidy, Q Zhang, DJ Morrison, T Preston, PA Kroon,... The American journal of clinical nutrition 97 (5), 995-1003
Phenolic metabolites of anthocyanins modulate mechanisms of endothelial function, M Edwards, C Czank, GM Woodward, A Cassidy, CD Kay. Journal of agricultural and food chemistry 63 (9), 2423-2431
The pharmacokinetics of anthocyanins and their metabolites in humans. RM Ferrars, C Czank, Q Zhang, NP Botting, PA Kroon, A Cassidy, CD Kay. British journal of pharmacology 171 (13), 3268-3282
Retention of the immunological proteins of pasteurized human milk in relation to pasteurizer design and practice. C Czank, DK Prime, B Hartmann, K Simmer, PE Hartmann. Pediatric research 66 (4), 374-37
Methods for isolating, identifying, and quantifying anthocyanin metabolites in clinical samples. RM de Ferrars, C Czank, S Saha, PW Needs, Q Zhang, KS Raheem, ...Analytical chemistry 86 (20), 10052-10058
BSc (Hons), Dip H Ed (Nursing), Grad Cert (Diab Edu)
Clinical research co-ordinator
Niru graduated in 1980 from the University of Malaya, and worked as a biochemist until she moved to England. After a few years break from working life, she studied to become a children's nurse and worked in Barnet General Hospital, England. Niru moved to Australia in 1997 and joined PMH as a registered nurse in 1998. She joined the Department of Endocrinology and Diabetes as a research nurse and diabetes educator in 2003.
Niru has been the clinical research co-ordinator for the team since 2004. She is actively involved in studies investigating the effect of exercise on children and youth with diabetes. Her other interests are the epidemiology of diabetes and technological advances in diabetes management.
Skladnev V, Ghevondian N, Tarnavskii, Paramalingam N, Jones T. Clinical Evaluation of a Non-Invasive Alarm System for Nocturnal Hypoglycaemia. J of Diabetes Science and Technology, 4(1): 67-74, 2010
Siafarikas A, Ratnam N, Baker V, Marangou D, Loveday J, LePage M, Elliott J, Bulsara MK, Jones TW, Davis EA (2007): The glucagon response to hypoglycaemia is lost early in adolescents with type 1 diabetes mellitus and not preserved by strict glycaemic control initiated at diagnosis. Pediatric Diabetes 8(Suppl 7):19
Bell LM, Watts K, Siafarikas A, Thompson A, Ratnam N, Bulsara M, Finn J, O'Driscoll G, Green D, Jones TW, Davis EA. Exercise alone reduces insulin resistance in obese children independently of changes in body composition. Journal of Clinical Endocrinology and Metabolism 92(11): 4230-4235, 2007
Guelfi K, Ratnam N, Smythe G, Jones TW, Fournier P. Effect of intermittent high-intensity compared to continuous moderate exercise on glucose production and utilization in individuals with type 1diabetes. American Journal of Physiology Endocrinology Metabolism 292(3), E865-870, 2007.
McMahon SK, Ferreira LD, Ratnam N, Davey RJ, Youngs LM, Davis EA, Fournier PA, Davis EA,, Fournier PA, Jones TW. Glucose requirements to maintain euglycaemia following moderate intensity afternoon exercise in adolescents with type 1 diabetes are increased in a biphasic manner. Journal of Clinical Endocrinology and Metabolism 92(3), 963-968, 2007
Bell LM, Byrne S, Thompson A, Ratnam N, Blair E, Bulsara M, Jones TW, Davis EA. Increasing BMI-Z Score is continuously associated with complications of overweight in children, even in the healthy range. Journal of Clinical Endocrinology and Metabolism 92(2), 517-522, 2007.
McMahon, S. K.,Haynes, A., Ratnam, N., Grant, M. T, Carne, C. L., Jones, T. W., Davis, E. A Increase in type 2 diabetes in children and adolescents in Western Australia. Medical Journal of Australia. Vol 180, No 9. pp 459-61, 2004.